GetReal Glossary of Key Terms

Terms of key relevance to GetReal

The table below contains definitions of key terms relevant to the IMI-GetReal Consortium.

The GetReal glossary working group acknowledges there is a debate around many of these terms, and in some cases no clear consensus has been reached in the international community. However, for the purpose of IMI-GetReal these are the proposed definitions

Please note: the definitions presented here are the result of several rounds of consultation. More specifically, definitions in previous versions of the glossary have been subjected to: an internal GetReal consultation round for consortium members in 2015, a public consultation round for external stakeholders in 2015, as well as second internal GetReal consultation round in 2016. For readers interested in the comments received during these rounds as well as authors’ replies, please see the full IMI-GetReal Glossary Report here.

GetReal Trial Tool

The GetReal Trial Tool is a decision support tool to assess the impact of design choices on generalizability of clinical trials to routine clinical practice, while taking into account the risk of bias, precision, acceptability and operational feasibility. This study describes the validation of the GetReal Trial Tool.

Real-World Evidence Navigator

The RWE Navigator is an output of the IMI GetReal project. GetReal aimed to show how robust new methods of real-world evidence (RWE) collection and synthesis could be adopted earlier in pharmaceutical research and development (R&D) and the healthcare decision-making process.

Real-World Evidence Study Design Landscape Tool

An online-tool to support the selection of RWE Study Designs, appropriate for the research question and stakeholders’ evidence needs.