Resources

Innovative and well-designed tools and resources to support the use and accessibility of Real-World Evidence

RWE Navigator

The RWE Navigator is an output of the IMI GetReal project. GetReal aimed to show how robust new methods of real-world evidence (RWE) collection and synthesis could be adopted earlier in pharmaceutical research and development (R&D) and the healthcare decision-making process.

GetReal Trial Tool

The GetReal Trial Tool is a decision support tool to assess the impact of design choices on generalizability of clinical trials to routine clinical practice, while taking into account the risk of bias, precision, acceptability and operational feasibility. This study describes the validation of the GetReal Trial Tool.

Related publications

Boateng, D., Kumke, T., Vernooij, R., Goetz, I., Meinecke, A. K., Steenhuis, C., Grobbee, D., Zuidgeest, M. G. P., & GetReal Initiative (2023). Validation of the GetReal Trial Tool – Facilitating discussion and understanding more pragmatic design choices and their implications. Contemporary clinical trials, 125, 107054.

Zuidgeest, M. G. P., Goetz, I., Meinecke, A. K., Boateng, D., Irving, E. A., van Thiel, G. J. M., Welsing, P. M. J., Oude-Rengerink, K., Grobbee, D. E., & www.imi-getreal.eu (2022). The GetReal Trial Tool: design, assess and discuss clinical drug trials in light of Real World Evidence generation. Journal of clinical epidemiology, 149, 244–253.

Real-World Evidence Study Design Landscape Tool

An online-tool to support the selection of RWE Study Designs, appropriate for the research question and stakeholders’ evidence needs.

This project was funded by the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 807012. This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA.

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